The Genomic Landscape of Vulvar Squamous Cell Carcinoma.

doi:10.1097/PGP.0000000000000950

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Article

The Genomic Landscape of Vulvar Squamous Cell Carcinoma.

International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists - 1 Sept 2023

Corey Logan, Wallbillich John J, Wu Sharon, Farrell Alex, Hodges Kurt, Xiu Joanne, Nabhan Chadi, Guastella Anthony, Kheil Mira, Gogoi Radhika, Winer Ira, Bandyopadhyay Sudeshna, Huang Marilyn, Jones Nathaniel, Wilhite Annelise, Karnezis Anthony, Thaker Premal, Herzog Thomas J, Oberley Matthew, Korn William Michael, Vezina Alex, Morris Robert, Ali-Fehmi Rouba

Abstract excerpt

Vulvar squamous cell cancer (VSC) accounts for 90% of vulvar cancers. Next-generation sequencing studies of VSC imply human papillomavirus (HPV) and p53 status play separate roles in carcinogenesis and prognosis. We sought to describe the genomic landscape and analyze the immunologic profiles of VSC with respect to HPV and p53 status. A total of 443 VSC tumors underwent tumor profiling. Next-generation sequencing...

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PMID: 37131274
DOI: 10.1097/PGP.0000000000000950
PMCID: PMC10417246

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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