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Article

Comprehensive Genomic Profiling of Metastatic Squamous Cell Carcinoma of the Anal Canal.

Molecular cancer research : MCR - 1 Nov 2017

Morris Van, Rao Xiayu, Pickering Curtis, Foo Wai Chin, Rashid Asif, Eterovic Karina, Kim Taebeom, Chen Ken, Wang Jing, Shaw Kenna, Eng Cathy

Abstract excerpt

Squamous cell carcinoma of the anal canal (SCCA) is a rare gastrointestinal malignancy with an increasing annual incidence globally. The majority of cases are linked to prior infection with the human papillomavirus (HPV). For patients with metastatic SCCA, no consensus standard treatment exists. Identification of relevant targeted agents as novel therapeutic approaches for metastatic SCCA has been limited by a...

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Identifiers

PMID: 28784613
DOI: 10.1158/1541-7786.MCR-17-0060
PMCID: PMC5991496

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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