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Article

DNA mismatch repair preferentially safeguards actively transcribed genes.

DNA repair - 1 Nov 2018

Huang Yaping, Li Guo-Min

Abstract excerpt

DNA mismatch repair (MMR) is an evolutionally conserved genome maintenance pathway and is well known for its role in maintaining replication fidelity by correcting biosynthetic errors generated during DNA replication. However, recent studies have shown that MMR preferentially protects actively transcribed genes from mutation during both DNA replication and transcription. This review describes the recent...

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Identifiers

PMID: 30174300
DOI: 10.1016/j.dnarep.2018.08.010
PMCID: PMC6340717

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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