Article
Genome-wide Escherichia coli stress response and improved tolerance towards industrially relevant chemicals.
Microbial cell factories - 13 Oct 2016
Rau Martin Holm, Calero Patricia, Lennen Rebecca M, Long Katherine S, Nielsen Alex T
Abstract excerpt
BACKGROUND: Economically viable biobased production of bulk chemicals and biofuels typically requires high product titers. During microbial bioconversion this often leads to product toxicity, and tolerance is therefore a critical element in the engineering of production strains. RESULTS: Here, a systems biology approach was employed to understand the chemical stress response of Escherichia coli, including a...
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