Article
Growth of E. coli on formate and methanol via the reductive glycine pathway.
Nature chemical biology - 1 May 2020
Kim Seohyoung, Lindner Steffen N, Aslan Selçuk, Yishai Oren, Wenk Sebastian, Schann Karin, Bar-Even Arren
Abstract excerpt
Engineering a biotechnological microorganism for growth on one-carbon intermediates, produced from the abiotic activation of CO2, is a key synthetic biology step towards the valorization of this greenhouse gas to commodity chemicals. Here we redesign the central carbon metabolism of the model bacterium Escherichia coli for growth on one-carbon compounds using the reductive glycine pathway. Sequential genomic...
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