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Article

Programmable T7-based synthetic transcription factors.

Nucleic acids research - 12 Oct 2018

Hussey Brendan J, McMillen David R

Abstract excerpt

Despite recent progress on synthetic transcription factor generation in eukaryotes, there remains a need for high-activity bacterial versions of these systems. In synthetic biology applications, it is useful for transcription factors to have two key features: they should be orthogonal (influencing only their own targets, with minimal off-target effects), and programmable (able to be directed to a wide range of...

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Identifiers

PMID: 30169636
DOI: 10.1093/nar/gky785
PMCID: PMC6182181

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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