Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CELL FATE DETERMINATION IN 3D: REGULATION OF GENE EXPRESSION VIA CHROMATIN INTERACTIONS WITH THE NUCLEAR MEMBRANE.

Transactions of the American Clinical and Climatological Association - 1 Jan 2018

Epstein Jonathan A

Abstract excerpt

In the nucleus of all cells, DNA is packaged in association with histone proteins to form chromatin. It is becoming increasingly clear that the organization of chromatin in three dimensions within the nucleus is highly regulated and can contribute to gene expression and cell function. The regions of the genome that are near the nuclear periphery are termed "lamin associated domains" or LADs (1-3). Here, I present...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Lineage
Share to Chromatin
Share to Chromatin Assembly and Disassembly

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histone Deacetylases

Share to Histones

Share to Myocytes, Cardiac

Share to Nuclear Envelope

Share to Transcriptional Activation

Source

Open in PubMed Open full text

Identifiers

PMID: 30166706
PMCID: PMC6116621

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CELL FATE DETERMINATION IN 3D: REGULATION OF GENE EXPRESSION VIA CHROMATIN INTERACTIONS WITH THE NUCLEAR MEMBRANE.PMID 30166706Read ↗

Lamin C regulates genome organization after mitosisSemantic proximity Read ↗

Pushing the envelope: developmental regulation by the nuclear lamina.Semantic proximity Read ↗

Lamins organize the global three-dimensional genome from the nuclear peripherySemantic proximity Read ↗

The nuclear lamins: flexibility in function.Semantic proximity Read ↗

The 3D nuclear position and compartmentalization of genes prime their response to mechano-confinementSemantic proximity Read ↗

An atlas of lamina-associated chromatin across twelve human cell types reveals an intermediate chromatin subtypeSemantic proximity Read ↗

Beyond A and B Compartments: how major nuclear locales define nuclear genome organization and functionSemantic proximity Read ↗

Architectural epigenetics: mitotic retention of mammalian transcriptional regulatory information.Semantic proximity Read ↗

Spatial 3D genome organization controls the activity of bivalent chromatin during human neurogenesisSemantic proximity Read ↗

Lamin A/C as a Molecular Link Between Nuclear Organization, Chromatin Dynamics, and Tumor ProgressionSemantic proximity Read ↗

Lamin A/C maintains genome topology and regulates transcriptional programs essential for virus-driven B cell activationSemantic proximity Read ↗

Networking in the nucleus: a spotlight on LEM-domain proteins.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.