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Article

Self-replication of circular DNA by a self-encoded DNA polymerase through rolling-circle replication and recombination.

Scientific reports - 30 Aug 2018

Sakatani Yoshihiro, Yomo Tetsuya, Ichihashi Norikazu

Abstract excerpt

A major challenge in constructing artificial cells is the establishment of a recursive genome replication system coupled with gene expression from the genome itself. One of the simplest schemes of recursive DNA replication is the rolling-circle replication of a circular DNA coupled with recombination. In this study, we attempted to develop a replication system based on this scheme using self-encoded phi29 DNA...

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Share to DNA, Circular
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 30166584
DOI: 10.1038/s41598-018-31585-1
PMCID: PMC6117322

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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