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Article

Rolling circle amplification: a versatile tool for chemical biology, materials science and medicine

1 Jan 2014

Abstract excerpt

Rolling circle amplification (RCA) is an isothermal enzymatic process where a short DNA or RNA primer is amplified to form a long single stranded DNA or RNA using a circular DNA template and special DNA or RNA polymerases. The RCA product is a concatemer containing tens to hundreds of tandem repeats that are complementary to the circular template. The power, simplicity, and versatility of the DNA amplification...

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PMID: 24643375
DOI: 10.1039/c3cs60439j

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