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Article

Genetic variations in CYP2A6, CYP2E1, GSTM1, GSTT1 genes and the risk of Nasopharyngeal carcinoma in North African population.

Annals of human genetics - 1 Jul 2025

Alami Imane El, Khaali Wafa, Jalbout Majida, Gihbid Amina, Ayoub Wided Ben, Benider Abdellatif, Brahim Selma Mohamed, Cherif Mokhtar Hamdi, Benchakroun Nadia, Mzibri Mohammed El, Driss El Khalil Ben, Belghmi Khalid, Corbex Marilys, Khyatti Meriem

Abstract excerpt

BACKGROUND: Nasopharyngeal carcinoma (NPC) is a multifactorial malignancy associated with both genetic and environmental factors. Polymorphic deletions of the phase I and phase II genes involved in the detoxification of potential carcinogens may be a risk factor for nasopharyngeal carcinoma. In this study, we investigated the relationship between CYP2E1 (rs3813867), CYP2A6, GSTM1(rs1183423000) and...

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Source

Identifiers

PMID: 38622954
DOI: 10.1111/ahg.12562

Genes

CYP2A6
CYP2E1
GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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