Article
XRCC1 and hOGG1 genes and risk of nasopharyngeal carcinoma in North African countries.
Molecular carcinogenesis - 1 Sept 2011
Laantri Nadia, Jalbout Majida, Khyatti Meriem, Ayoub Wided Ben, Dahmoul Sami, Ayad Messaoud, Bedadra Wided, Abdoun Meriem, Mesli Sarah, Kandil Mostafa, Hamdi-Cherif Mokhtar, Boualga Kada, Bouaouina Noureddine, Chouchane Lotfi, Benider Abdellatif, Ben-Ayed Farhat, Goldgar David, Corbex Marilys
Abstract excerpt
Although genetic susceptibility to nasopharyngeal carcinoma (NPC) has been recognized for a long time, little is known about the responsible genes. X-Ray repair cross-complementing protein 1 (XRCC1) and human 8-oxo-guanine glycosylase 1 (hOGG1) genes are involved in deoxyribonucleic acid (DNA) repair and were found associated with NPC risk in three Asian case-control studies. The objective of the present study...
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