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Article

Genetic Polymorphisms in ERCC1 Gene and Their Association with Response to Radiotherapy in Moroccan Patients with Nasopharyngeal Carcinoma.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2023

Benzeid Rajaa, Gihbid Amina, Tawfiq Nezha, Benchakroun Nadia, Bendahhou Karima, Benider Abdelatif, Guensi Amal, El Benna Naima, Filali Maltouf Abdelkarim, Attaleb Mohammed, Chaoui Imane, Khyatti Meriem, El Mzibri Mohammed

Abstract excerpt

OBJECTIVE: Nasopharyngeal carcinoma (NPC) is a severe malignant disease. Despite its low frequency, NPC is very common in North African population. Radiotherapy is the standard therapeutic treatment of NPC. However, radioresistance hampers the success of treatment. At the molecular scale, radioresistance is due to genetic variations involved in DNA repair pathways in NPC patients. Several studies reported that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36708557
DOI: 10.31557/APJCP.2023.24.1.93
PMCID: PMC10152845

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