Article
No association between TGF-β1 polymorphisms and risk of nasopharyngeal carcinoma in a large North African case-control study.
BMC medical genetics - 12 Oct 2016
Khaali Wafa, Moumad Khalid, Ben Driss El Khalil, Benider Abdellatif, Ben Ayoub Wided, Hamdi-Cherif Mokhtar, Boualga Kada, Hassen Elham, Corbex Marilys, Khyatti Meriem
Abstract excerpt
BACKGROUND: Genetic susceptibility plays a key role in the development of nasopharyngeal carcinoma (NPC) and in fact the disease presents with an unusually high incidence in certain regions of the world like North Africa. We investigated the association between polymorphism of the Transforming growth factor-β1 (TGF-β1) and risk of NPC in North Africa. TGF-β1 is a multifunctional cytokine that acts as both a tumor...
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