Article
The CC-genotype of the cyclooxygenase-2 gene associates with decreased risk of nasopharyngeal carcinoma in a Tunisian population.
Pathologie-biologie - 1 Feb 2015
Mamoghli T, Douik H, Mehri S, Ghanem A, Ben Chaabane A, Bouassida J, Kablouti G, Harzallah L, Gritli S, Guemira F
Abstract excerpt
BACKGROUND: The cyclooxygenase-2 (cox-2) pathway is now recognized to be important in human cancer development and progression. The gene for cox-2 carries a common single nucleotide polymorphism, T8473C, located within a potential functional region in the 3'-UTR of cox-2 gene was identified. We have investigated the frequencies of cox-2 genotypes in Tunisian population to determine whether that polymorphism was...
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