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Article

Association analysis of exome variants and refraction, axial length, and corneal curvature in a European-American population.

Human mutation - 1 Dec 2018

Vergara Candelaria, Bomotti Samantha M, Valencia Cristian, Klein Barbara E K, Lee Kristine E, Klein Ronald, Klein Alison P, Duggal Priya

Abstract excerpt

Refractive errors, myopia, and hyperopia are common visual disorders greatly affecting older individuals. Refraction is determined by genetic factors but only a small percentage of its variation has been explained. We performed a genetic association analysis with three ocular phenotypes: spherical equivalent (a continous measure of refraction), axial length, and corneal curvature in 1,871 European-Americans from...

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Identifiers

PMID: 30157304
DOI: 10.1002/humu.23628
PMCID: PMC6497529

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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