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Article

MERIT: Systematic Analysis and Characterization of Mutational Effect on RNA Interactome Topology.

Hepatology (Baltimore, Md.) - 1 Aug 2019

Li Yongsheng, McGrail Daniel J, Xu Juan, Li Junyi, Liu Ning-Ning, Sun Ming, Lin Richard, Pancsa Rita, Zhang Jiwei, Lee Ju-Seog, Wang Hui, Mills Gordon B, Li Xia, Yi Song, Sahni Nidhi

Abstract excerpt

The interaction between RNA-binding proteins (RBPs) and RNA plays an important role in regulating cellular function. However, decoding genome-wide protein-RNA regulatory networks as well as how cancer-related mutations impair RNA regulatory activities in hepatocellular carcinoma (HCC) remains mostly undetermined. We explored the genetic alteration patterns of RBPs and found that deleterious mutations are likely...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 30153342
DOI: 10.1002/hep.30242
PMCID: PMC6538468

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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