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Article

Elevated methylation of OPRM1 and OPRL1 genes in Alzheimer's disease.

Molecular medicine reports - 1 Nov 2018

Xu Chunshuang, Liu Guili, Ji Huihui, Chen Weihua, Dai Dongjun, Chen Zhongming, Zhou Dongsheng, Xu Lei, Hu Haochang, Cui Wei, Chang Lan, Zha Qin, Li Liping, Duan Shiwei, Wang Qinwen

Abstract excerpt

Previous studies have suggested that increased opioid receptor κ1 (OPRK1) and opioid receptor δ1 (OPRD1) methylation levels are involved in Alzheimer's disease (AD). In the present study, the methylation levels of two opioid receptor genes, opioid receptor µ1 (OPRM1) and opioid related nociceptin receptor 1 (OPRL1), were analyzed for their association with AD. Gene methylation levels were measured using bisulfite...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 30152845
DOI: 10.3892/mmr.2018.9424
PMCID: PMC6172396

Genes

OPRL1
OPRM1
OPRD1
OPRK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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