Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

OPRD1 Genetic Variation and Human Disease.

Handbook of experimental pharmacology - 1 Jan 2000

Crist Richard C, Clarke Toni-Kim

Abstract excerpt

The OPRD1 gene encodes the delta-opioid receptor, which has multiple functions including regulating reward pathways. The gene contains more than 2,000 verified genetic variants but only 2 currently have evidence for specific functions: rs1042114 disrupts maturation of the receptor and rs569356 affects OPRD1 expression. These polymorphisms and others in the gene have been found to be associated with human...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Feeding and Eating Disorders

Share to Genetic Variation

Share to Obesity

Share to Opioid-Related Disorders

Share to Receptors, Opioid, delta

Source

Identifiers

PMID: 28035534
DOI: 10.1007/164_2016_112

Genes

OPRD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

OPRD1 Genetic Variation and Human Disease.PMID 28035534Read ↗

Genetic and Epigenetic Approaches to Opioid Use Disorder.Semantic proximity Read ↗

Variant detection at the delta opioid receptor (OPRD1) locus and population genetics of a novel variant affecting protein sequence.Semantic proximity Read ↗

Association of OPRD1 Gene Variants with Opioid Dependence in Addicted Male Individuals Undergoing Methadone Treatment in the North of IranSemantic proximity Read ↗

Genetic Variants Linked to Opioid Addiction: A Genome Wide Association StudySemantic proximity Read ↗

Association of polymorphisms in pharmacogenetic candidate genes (OPRD1, GAL, ABCB1, OPRM1) with opioid dependence in European population: a case-control study.Semantic proximity Read ↗

Genetic Variants Linked to Opioid Addiction: A Genome-Wide Association Study.Semantic proximity Read ↗

Functional genetics reveals the contribution of delta opioid receptor to type 2 diabetes and beta-cell functionSemantic proximity Read ↗

Overview of genetic analysis of human opioid receptors.Semantic proximity Read ↗

Overview of Genetic Analysis of Human Opioid Receptors.Semantic proximity Read ↗

Functional impact of a single-nucleotide polymorphism in the OPRD1 promoter region.Semantic proximity Read ↗

A commonly carried genetic variant in the delta opioid receptor gene, OPRD1, is associated with smaller regional brain volumes: replication in elderly and young populations.Semantic proximity Read ↗

Case-control association analysis of polymorphisms in the δ-opioid receptor, OPRD1, with cocaine and opioid addicted populations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.