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Article

Centrin depletion causes cyst formation and other ciliopathy-related phenotypes in zebrafish.

Cell cycle (Georgetown, Tex.) - 15 Nov 2011

Delaval Benedicte, Covassin Laurence, Lawson Nathan D, Doxsey Stephen

Abstract excerpt

Most bona fide centrosome proteins including centrins, small calcium-binding proteins, participate in spindle function during mitosis and play a role in cilia assembly in non-cycling cells. Although the basic cellular functions of centrins have been studied in lower eukaryotes and vertebrate cells in culture, phenotypes associated with centrin depletion in vertebrates in vivo has not been directly addressed. To...

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Identifiers

PMID: 22142866
DOI: 10.4161/cc.10.22.18150
PMCID: PMC3266121

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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