Article
Phenotypic Lentivirus Screens to Identify Antiviral Single Domain Antibodies.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2018
Schmidt Florian Ingo
Abstract excerpt
Our understanding of infection biology is based on experiments in which pathogen or host proteins are perturbed by small compound inhibitors, mutation, or depletion. This approach has been remarkably successful, as, for example, demonstrated by the independent identification of the endosomal membrane protein Niemann-Pick C1 as an essential factor for Ebola virus infection in both small compound and insertional...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
