Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expanding and improving nanobody repertoires using a yeast display method: Targeting SARS-CoV-2

28 Jan 2023

Abstract excerpt

COVID-19, caused by the coronavirus SARS-CoV-2, represents a serious worldwide health issue, with continually emerging new variants challenging current therapeutics. One promising alternate therapeutic avenue is represented by nanobodies, small single-chain antibodies derived from camelids with numerous advantageous properties and the potential to neutralize the virus. For identification and characterization of a...

Topics

Join the communities discussing this publication.

Cell Image Analysis Techniques
SARS-CoV-2 and COVID-19 Research
Transgenic Plants and Applications

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 36720309
DOI: 10.1016/j.jbc.2023.102954

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expanding and improving nanobody repertoires using a yeast display method: Targeting SARS-CoV-2PMID 36720309Read ↗

Biparatopic nanobodies targeting the receptor binding domain efficiently neutralize SARS-CoV-2Semantic proximity Read ↗

Rapid generation of potent antibodies by autonomous hypermutation in yeastSemantic proximity Read ↗

A cell-free nanobody engineering platform rapidly generates SARS-CoV-2 neutralizing nanobodiesSemantic proximity Read ↗

Versatile, Multivalent Nanobody Cocktails Efficiently Neutralize SARS-CoV-2Semantic proximity Read ↗

Nanobody Repertoires for Exposing Vulnerabilities of SARS-CoV-2Semantic proximity Read ↗

Selection, biophysical and structural analysis of synthetic nanobodies that effectively neutralize SARS-CoV-2Semantic proximity Read ↗

Engineered Multivalent Nanobodies Potently and Broadly Neutralize SARS‐CoV‐2 VariantsSemantic proximity Read ↗

Multivariate mining of an alpaca immune repertoire identifies potent cross-neutralizing SARS-CoV-2 nanobodiesSemantic proximity Read ↗

Structure-guided in vitro evolution of nanobodies targeting new viral variants.Semantic proximity Read ↗

Highly synergistic combinations of nanobodies that target SARS-CoV-2 and are resistant to escapeSemantic proximity Read ↗

Synthetic repertoires derived from convalescent COVID-19 patients enable discovery of SARS-CoV-2 neutralizing antibodies and a novel quaternary binding modalitySemantic proximity Read ↗

Nanobody engineering for SARS-CoV-2 neutralization and detectionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.