Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Period protein homolog LIN-42 regulates germline development in C. elegans.

Mechanisms of development - 1 Oct 2018

Berardi Skyler, McFall Alanna, Toledo-Hernandez Amanda, Coote Carolyn, Graham Hillary, Stine Laurel, Rhodehouse Kyle, Auernhamer Anna, Van Wynsberghe Priscilla M

Abstract excerpt

Germline stem cells are maintained in the distal region of the C. elegans gonad. These cells undergo mitotic divisions, and GLP-1/Notch signaling dictates whether they remain in this state. The somatic distal tip cell (DTC) caps the end of the distal gonad and is essential for maintenance of the germline mitotic zone. As germ cells move away from the DTC they exit mitosis and enter early meiotic prophase. Here we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caenorhabditis elegans
Share to Caenorhabditis elegans Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Developmental

Share to Germ Cells

Share to Mitosis

Share to Period Circadian Proteins

Share to Receptors, Notch

Share to Transcription, Genetic

Source

Identifiers

PMID: 30144508
DOI: 10.1016/j.mod.2018.08.008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Period protein homolog LIN-42 regulates germline development in C. elegans.PMID 30144508Read ↗

Novel heterochronic functions of the Caenorhabditis elegans period-related protein LIN-42.Semantic proximity Read ↗

Similarity of the C. elegans developmental timing protein LIN-42 to circadian rhythm proteins.Semantic proximity Read ↗

Cyclin E and CDK-2 regulate proliferative cell fate and cell cycle progression in the <i>C. elegans</i> germlineSemantic proximity Read ↗

The establishment of Caenorhabditis elegans germline pattern is controlled by overlapping proximal and distal somatic gonad signals.Semantic proximity Read ↗

Analysis of a lin-42/period Null Allele Implicates All Three Isoforms in Regulation of Caenorhabditis elegans Molting and Developmental Timing.Semantic proximity Read ↗

LIN-42/PERIOD controls cyclical and developmental progression of C. elegans molts.Semantic proximity Read ↗

Germline proliferation and its controlSemantic proximity Read ↗

Caenorhabditis elegans period homolog lin-42 regulates the timing of heterochronic miRNA expression.Semantic proximity Read ↗

A Genome-Wide RNAi Screen for Enhancers of a Germline Tumor Phenotype Caused by Elevated GLP-1/Notch Signaling in Caenorhabditis elegans.Semantic proximity Read ↗

Analysis of Germline Stem Cell Differentiation Following Loss of GLP-1 Notch Activity in Caenorhabditis elegansSemantic proximity Read ↗

Non-autonomy of age-related morphological changes in the C. elegans germline stem cell niche.Semantic proximity Read ↗

A DTC Niche Plexus Surrounds the Germline Stem Cell Pool in Caenorhabditis elegansSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.