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Article

Cyclin E and CDK-2 regulate proliferative cell fate and cell cycle progression in the <i>C. elegans</i> germline

10 May 2011

Abstract excerpt

The C. elegans germline provides an excellent model for analyzing the regulation of stem cell activity and the decision to differentiate and undergo meiotic development. The distal end of the adult hermaphrodite germline contains the proliferative zone, which includes a population of mitotically cycling cells and cells in meiotic S phase, followed by entry into meiotic prophase. The proliferative fate is...

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PMID: 21558371
DOI: 10.1242/dev.059535

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