Article
Analysis of a lin-42/period Null Allele Implicates All Three Isoforms in Regulation of Caenorhabditis elegans Molting and Developmental Timing.
G3 (Bethesda, Md.) - 7 Dec 2016
Edelman Theresa L B, McCulloch Katherine A, Barr Angela, Frøkjær-Jensen Christian, Jorgensen Erik M, Rougvie Ann E
Abstract excerpt
The Caenorhabditis elegans heterochronic gene pathway regulates the relative timing of events during postembryonic development. lin-42, the worm homolog of the circadian clock gene, period, is a critical element of this pathway. lin-42 function has been defined by a set of hypomorphic alleles that cause precocious phenotypes, in which later developmental events, such as the terminal differentiation of hypodermal...
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