Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Caenorhabditis elegans period homolog lin-42 regulates the timing of heterochronic miRNA expression.

Proceedings of the National Academy of Sciences of the United States of America - 28 Oct 2014

McCulloch Katherine A, Rougvie Ann E

Abstract excerpt

MicroRNAs (miRNAs) are small RNAs that regulate gene expression posttranscriptionally via the 3' UTR of target mRNAs and were first identified in the Caenorhabditis elegans heterochronic pathway. miRNAs have since been found in many organisms and have broad functions, including control of differentiation and pluripotency in humans. lin-4 and let-7-family miRNAs regulate developmental timing in C. elegans, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caenorhabditis elegans
Share to Caenorhabditis elegans Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epistasis, Genetic

Share to Green Fluorescent Proteins

Share to MicroRNAs

Share to Multigene Family

Share to Period Circadian Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 25319259
DOI: 10.1073/pnas.1414856111
PMCID: PMC4217435

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Caenorhabditis elegans period homolog lin-42 regulates the timing of heterochronic miRNA expression.PMID 25319259Read ↗

LIN-42, the Caenorhabditis elegans PERIOD homolog, negatively regulates microRNA transcription.Semantic proximity Read ↗

The Period protein homolog LIN-42 negatively regulates microRNA biogenesis in C. elegans.Semantic proximity Read ↗

let-7 miRNA and lin-46 mRNA are essential targets of the LIN28 RNA-binding protein in Caenorhabditis elegans developmental timing regulation.Semantic proximity Read ↗

Novel heterochronic functions of the Caenorhabditis elegans period-related protein LIN-42.Semantic proximity Read ↗

Similarity of the C. elegans developmental timing protein LIN-42 to circadian rhythm proteins.Semantic proximity Read ↗

<i>C. elegans</i> LIN-28 controls temporal cell-fate progression by regulating LIN-46 expression via the 5’UTR of <i>lin-46</i> mRNASemantic proximity Read ↗

Developmental timing in C. elegans is regulated by kin-20 and tim-1, homologs of core circadian clock genes.Semantic proximity Read ↗

Misexpression of the Caenorhabditis elegans miRNA let-7 is sufficient to drive developmental programs.Semantic proximity Read ↗

Analysis of a lin-42/period Null Allele Implicates All Three Isoforms in Regulation of Caenorhabditis elegans Molting and Developmental Timing.Semantic proximity Read ↗

C. elegans LIN-28 controls temporal cell fate progression by regulating LIN-46 expression via the 5' UTR of lin-46 mRNA.Semantic proximity Read ↗

A developmental timer coordinates organism-wide microRNA transcriptionSemantic proximity Read ↗

The Period protein homolog LIN-42 regulates germline development in C. elegans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.