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A DTC Niche Plexus Surrounds the Germline Stem Cell Pool in Caenorhabditis elegans

19 Feb 2014

Abstract excerpt

The mesenchymal distal tip cell (DTC) provides the niche for Caenorhabditis elegans germline stem cells (GSCs). The DTC has a complex cellular architecture: its cell body caps the distal gonadal end and contacts germ cells extensively, but it also includes multiple cellular processes that extend along the germline tube and intercalate between germ cells. Here we use the lag-2 DTC promoter to drive expression of...

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PMID: 24586318
DOI: 10.1371/journal.pone.0088372

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