Chronic hepatitis D in Austria: high burden of cirrhosis and portal hypertension, IL28B C/C as unfavorable factor, increased systemic inflammation in decompensation.

doi:10.1007/s00508-026-02700-4

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Chronic hepatitis D in Austria: high burden of cirrhosis and portal hypertension, IL28B C/C as unfavorable factor, increased systemic inflammation in decompensation.

Wiener klinische Wochenschrift - 1 Aug 2026

Schwarz Michael, Schwarz Caroline, Bauer David J M, Panzer Marlene, Hintersteininger Marlene, Strasser Michael, Reiter Silvia, Dorn Livia, Trauner Michael, Stättermayer Albert Friedrich, Mandorfer Mattias, Maieron Andreas, Moschen Alexander, Aigner Elmar, Zoller Heinz, Gschwantler Michael, Reiberger Thomas, Jachs Mathias

Abstract excerpt

INTRODUCTION: Chronic hepatitis D (CHD) is a severe viral hepatitis characterized by a rapid progression towards advanced chronic liver disease (ACLD). This study aimed to characterize the Austrian CHD epidemiology with respect to disease severity, systemic inflammation and genetic markers. METHODS: Patients attending one of six participating hospitals from 2020 onwards were included and assessed regarding...

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PMID: 41642318
DOI: 10.1007/s00508-026-02700-4
PMCID: PMC13493468

Genes

PNPLA3
SERPINA1

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