Article

<i>N</i> -linked glycosylation of the M-protein variable region: Glycoproteogenomics reveals a new layer of personalized complexity in multiple myeloma

2023-04-06

Abstract excerpt

<h4>ABSTRACT</h4> Multiple Myeloma (MM) is a plasma cell malignancy characterized by a monoclonal expansion of plasma cells that secrete a characteristic M-protein. This M-protein is crucial for diagnosis and monitoring of MM in the blood of patients. Recent evidence has emerged suggesting that N-glycosylation of the M-protein variable (Fab) region contributes to M-protein pathogenicity, and that it is a risk fac...

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Literature Corpus work: 0a7edbc1-e09f-5ea0-bf3c-4bb17353bc04
DOI: 10.1101/2023.04.05.535540

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