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Article

Prediction of LDL cholesterol response to statin using transcriptomic and genetic variation.

Genome biology - 30 Sept 2014

Kim Kyungpil, Bolotin Eugene, Theusch Elizabeth, Huang Haiyan, Medina Marisa W, Krauss Ronald M

Abstract excerpt

BACKGROUND: Statins are widely prescribed for lowering LDL-cholesterol (LDLC) levels and risk of cardiovascular disease. There is, however, substantial inter-individual variation in the magnitude of statin-induced LDLC reduction. To date, analysis of individual DNA sequence variants has explained...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hydroxymethylglutaryl-CoA Reductase Inhibitors

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Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 25316374
DOI: 10.1186/s13059-014-0460-9
PMCID: PMC4180544

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25316374-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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