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Article

Novel DNA Methylation Sites Influence GPR15 Expression in Relation to Smoking

20 Aug 2018

Abstract excerpt

Smoking is a major risk factor for cardiovascular diseases and has been implicated in the regulation of the G protein-coupled receptor 15 (GPR15) by affecting CpG methylation. The G protein-coupled receptor 15 is involved in angiogenesis and inflammation. An effect on GPR15 gene regulation has been shown for the CpG site CpG3.98251294. We aimed to analyze the effect of smoking on GPR15 expression and methylation...

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PMID: 30127295
DOI: 10.3390/biom8030074

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