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Article

Cigarette smoking behaviors and time since quitting are associated with differential DNA methylation across the human genome

6 Apr 2012

Abstract excerpt

The impact of cigarette smoking can persist for extended periods following smoking cessation and may involve epigenetic reprogramming. Changes in DNA methylation associated with smoking may help to identify molecular pathways that contribute to the latency between exposure and disease onset. Cross-sectional cohort data from subjects in the International COPD Genetics Network (n = 1085) and the Boston Early-Onset...

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PMID: 22492999
DOI: 10.1093/hmg/dds135

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