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Article

Genome-wide DNA methylation study identifies genes associated with the cardiovascular biomarker GDF-15

17 Dec 2015

Abstract excerpt

Growth-differentiation factor 15 (GDF-15) is expressed in low to moderate levels in most healthy tissues and increases in response to inflammation. GDF-15 is associated with cardiovascular dysfunction and over-expressed in the myocardium of patients with myocardial infarction (MI). However, little is known about the function of GDF-15 in cardiovascular disease, and the underlying regulatory network of GDF-15 is...

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PMID: 26681806
DOI: 10.1093/hmg/ddv511

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