Article
Genome-wide association analyses suggested a novel mechanism for smoking behavior regulated by IL15.
Molecular psychiatry - 1 Jul 2009
Liu Y-Z, Pei Y-F, Guo Y-F, Wang L, Liu X-G, Yan H, Xiong D-H, Zhang Y-P, Levy S, Li J, Haddock C K, Papasian C J, Xu Q, Ma J Z, Payne T J, Recker R R, Li M D, Deng H-W
Abstract excerpt
Cigarette smoking is the leading preventable cause of death in the United States. Although smoking behavior has a significant genetic determination, the specific genes and associated mechanisms underlying the smoking behavior are largely unknown. Here, we carried out a genome-wide association study on smoking behavior in 840 Caucasians, including 417 males and 423 females, in which we examined approximately...
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