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Article

Association study of Disrupted-In-Schizophrenia-1 gene variants and tardive dyskinesia.

Neuroscience letters - 1 Nov 2018

Lu Justin Y, Tiwari Arun K, Zai Gwyneth C, Rastogi Anjali, Shaikh Sajid A, Müller Daniel J, Voineskos Aristotle N, Potkin Steven G, Lieberman Jeffrey A, Meltzer Herbert Y, Remington Gary, Wong Albert H C, Kennedy James L, Zai Clement C

Abstract excerpt

Tardive dyskinesia (TD) is an involuntary movement disorder that occurs in ∼20% of patients after extended antipsychotic use. Its pathophysiology is unclear; however, familial patterns and gene association studies indicate an inherited component to risk. The disrupted in schizophrenia 1 (DISC1) gene was selected for analysis because it interacts with and regulates two important proteins involved in antipsychotic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 30118782
DOI: 10.1016/j.neulet.2018.08.007

Genes

DISC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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