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Article

Ca2+ and innate immune pathways are activated and differentially expressed in childhood asthma phenotypes.

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology - 1 Dec 2018

Boeck Andreas, Landgraf-Rauf Katja, Vogelsang Vanessa, Siemens Diana, Prazeres da Costa Olivia, Klucker Elisabeth, von Mutius Erika, Buch Thorsten, Mansmann Ulrich, Schaub Bianca

Abstract excerpt

BACKGROUND: Asthma is the most common chronic disease in children. Underlying immunologic mechanisms-in particular of different phenotypes-are still just partly understood. The objective of the study was the identification of distinct cellular pathways in allergic asthmatics (AA) and nonallergic asthmatics (NA) vs healthy controls (HC). METHODS: Peripheral blood mononuclear cells (PBMCs) of steroid-naïve children...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 30102794
DOI: 10.1111/pai.12971

Genes

FPR2
IFIH1
ORMDL3
TLR7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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