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Investigation of key ferroptosis-associated genes and potential therapeutic drugs for asthma based on machine learning and regression models

26 Jul 2025

Abstract excerpt

Bronchial asthma is a complex and heterogeneous disease, with ferroptosis, a form of non-apoptotic cell death, contributing to its pathogenesis by inducing airway epithelial damage, inflammatory infiltration, and airway remodeling. Investigating ferroptosis-related characteristic genes and potential therapeutic compounds may enhance asthma management. This study employed differential analysis and machine learning...

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PMID: 40715138
DOI: 10.1038/s41598-025-06122-6

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