Article

Single-cell RNA sequencing unraveled the expression heterogeneity of hematopoietic stem and progenitor cells and lymphoid cell development dysregulation in childhood asthma

2024-03-18

Abstract excerpt

Asthma is a long-term inflammatory disease affecting airways and lungs with usual onset in childhood. Its cause is not fully understood up to now. Here, using single-cell RNA sequencing, we profile peripheral blood mononuclear cells (PBMCs) from three pediatric patients with onset asthma and four age-matched healthy controls to investigate the cellular etiology of childhood asthma. The overall expression features...

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Literature Corpus work: 873ca823-376a-51e9-aec4-d57d68a1d8ee
DOI: 10.1101/2024.03.17.24304334

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