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Article

Derangement of cell cycle markers in peripheral blood mononuclear cells of asthmatic patients as a reliable biomarker for asthma control.

Scientific reports - 4 Jun 2021

Hachim Mahmood Yaseen, Elemam Noha Mousaad, Ramakrishnan Rakhee K, Salameh Laila, Olivenstein Ronald, Hachim Ibrahim Yaseen, Venkatachalam Thenmozhi, Mahboub Bassam, Al Heialy Saba, Hamid Qutayba, Hamoudi Rifat

Abstract excerpt

In asthma, most of the identified biomarkers pertain to the Th2 phenotype and no known biomarkers have been verified for severe asthmatics. Therefore, identifying biomarkers using the integrative phenotype-genotype approach in severe asthma is needed. The study aims to identify novel biomarkers as genes or pathways representing the core drivers in asthma development, progression to the severe form, resistance to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34088958
DOI: 10.1038/s41598-021-91087-5
PMCID: PMC8178351

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