Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fine-mapping analysis of a chromosome 2 region linked to resistance to Mycobacterium tuberculosis infection in Uganda reveals potential regulatory variants.

Genes and immunity - 1 Jul 2019

Igo Robert P, Hall Noémi B, Malone LaShaunda L, Hall Jacob B, Truitt Barbara, Qiu Feiyou, Tao Li, Mupere Ezekiel, Schnell Audrey, Hawn Thomas R, Bush William S, Joloba Moses, Boom W Henry, Stein Catherine M

Abstract excerpt

Tuberculosis (TB) is a major public health burden worldwide, and more effective treatment is sorely needed. Consequently, uncovering causes of resistance to Mycobacterium tuberculosis (Mtb) infection is of special importance for vaccine design. Resistance to Mtb infection can be defined by a persistently negative tuberculin skin test (PTST-) despite living in close and sustained exposure to an active TB case....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Mass Index
Share to Chromosomes, Human, Pair 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Resistance

Share to Glycosyltransferases

Share to Histone Deacetylase 1

Share to Tuberculosis

Share to Uganda

Share to Zinc Finger E-box Binding Homeobox 2

Source

Open in PubMed Open full text

Identifiers

PMID: 30100616
DOI: 10.1038/s41435-018-0040-1
PMCID: PMC6374218

Genes

ZEB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fine-mapping analysis of a chromosome 2 region linked to resistance to Mycobacterium tuberculosis infection in Uganda reveals potential regulatory variants.PMID 30100616Read ↗

Resistance to TST/IGRA conversion in Uganda: Heritability and Genome-Wide Association Study.Semantic proximity Read ↗

Methylome-wide analysis reveals epigenetic marks associated with resistance to tuberculosis in HIV-infected individuals from East AfricaSemantic proximity Read ↗

Genome scan of M. tuberculosis infection and disease in Ugandans.Semantic proximity Read ↗

Polymorphisms in TICAM2 and IL1B are associated with TB.Semantic proximity Read ↗

Genome-to-genome analysis reveals associations between human and mycobacterial genetic variation in tuberculosis patients from TanzaniaSemantic proximity Read ↗

Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11.2.Semantic proximity Read ↗

Genetic susceptibility to tuberculosis associated with cathepsin Z haplotype in a Ugandan household contact study.Semantic proximity Read ↗

Epigenetic programming of host lipid metabolism associates with resistance to TST/IGRA conversion after exposure to <i>Mycobacterium tuberculosis</i>Semantic proximity Read ↗

Genome-wide association study of resistance to Mycobacterium tuberculosis infection identifies a locus at 10q26.2 in three distinct populations.Semantic proximity Read ↗

Exploring the genetic factors behind the discrepancy in resistance to bovine tuberculosis between African zebu cattle and European taurine cattle.Semantic proximity Read ↗

<i>Mycobacterium tuberculosis</i>-dependent Monocyte Expression Quantitative Trait Loci and Tuberculosis PathogenesisSemantic proximity Read ↗

Genome-wide association study in Brazil identifies genetic susceptibility to tuberculosis with single-cell gene effectsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.