Article
Genetic susceptibility to tuberculosis associated with cathepsin Z haplotype in a Ugandan household contact study.
Human immunology - 1 May 2011
Baker Allison R, Zalwango Sarah, Malone LaShaunda L, Igo Robert P, Qiu Feiyou, Nsereko Mary, Adams Mark D, Supelak Pamela, Mayanja-Kizza Harriet, Boom W Henry, Stein Catherine M
Abstract excerpt
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), causes 9 million new cases worldwide and 2 million deaths annually. Genetic linkage and association analyses have suggested several chromosomal regions and candidate genes involved in TB susceptibility. This study examines the association of TB disease susceptibility with a selection of biologically relevant genes on regions on chromosomes 7 (IL6 and...
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