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Article

Polymorphisms in TICAM2 and IL1B are associated with TB.

Genes and immunity - 1 Mar 2015

Hall Noémi Borsay, Igo Robert P, Malone LaShaunda L, Truitt Barbara, Schnell Audrey, Tao Li, Okware Brenda, Nsereko Mary, Chervenak Keith, Lancioni Christina, Hawn Thomas R, Mayanja-Kizza Harriet, Joloba Moses L, Boom W Henry, Stein Catherine M

Abstract excerpt

Human genetic susceptibility for tuberculosis (TB) has been demonstrated by several studies, but few have examined the multiple innate and adaptive immunity genes comprehensively, age-specific effects and/or resistance to Mycobacterium tuberculosis (Mtb) infection (resistors (RSTRs)). We hypothesized that RSTRs, defined by a persistently negative tuberculin skin test, may have different genetic influences than...

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Source

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Identifiers

PMID: 25521228
DOI: 10.1038/gene.2014.77
PMCID: PMC4352113

Genes

TICAM2
NOD2
TLR4
TLR6
TOLLIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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