Article
Metabolic signature of squamous cell carcinoma of the head and neck: Consequences of TP53 mutation and therapeutic perspectives.
Oral oncology - 1 Aug 2018
Wilkie Mark D, Lau Andrew S, Vlatkovic Nikolina, Jones Terence M, Boyd Mark T
Abstract excerpt
There is a pressing need to identify ways of sensitising squamous cell carcinomas of the head and neck (SCCHN) to the effects of current treatments, both from oncological and functional perspectives. Alteration to cellular metabolism is now widely considered a hallmark of the cancer phenotype; presents a potentially attractive therapeutic target in this regard; and as such has received renewed research interest...
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