Article

Metabolic pathways fuelling Devil Facial Tumour Disease

2025-03-14

Abstract excerpt

<h4>ABSTRACT</h4> Devil Facial Tumour Diseases (DFTD), threatening Tasmanian devils, consist of two distinct transmissible cancers, DFT1 and DFT2, with differing origins and geographic spread. We investigated the metabolic differences between DFT1 and DFT2, examining cell viability, metabolic outputs, and bulk gene expression. Using both DFT1 and DFT2 cell lines and biopsies, we found that glycolysis, oxidative p...

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Literature Corpus work: 54b5cd9b-bd67-5070-9db0-b3e0f209b338
DOI: 10.1101/2025.03.12.642198

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