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HPV, tumour metabolism and novel target identification in head and neck squamous cell carcinoma

17 Jan 2019

Abstract excerpt

BACKGROUND: Metabolic changes in tumour cells are used in clinical imaging and may provide potential therapeutic targets. Human papillomavirus (HPV) status is important in classifying head and neck cancers (HNSCC), identifying a distinct clinical phenotype; metabolic differences between these HNSCC subtypes remain poorly understood. METHODS: HNSCC cell lines. The monocarboxylic acid transporter-1 (MCT1) was...

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PMID: 30655616
DOI: 10.1038/s41416-018-0364-7

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