Article
Association Study of CHRNA7 Promoter Variants with Sensory and Sensorimotor Gating in Schizophrenia Patients and Healthy Controls: A Danish Case-Control Study.
Neuromolecular medicine - 1 Dec 2015
Bertelsen Birgitte, Oranje Bob, Melchior Linea, Fagerlund Birgitte, Werge Thomas M, Mikkelsen Jens D, Tümer Zeynep, Glenthøj Birte Y
Abstract excerpt
Schizophrenia is a severe psychiatric disorder with a core component of impaired cognitive function still remaining as one of the greatest challenges in the pharmacological treatment of the disorder. The CHRNA7 gene, encoding the subunit of the human α7 nicotinic acetylcholine receptor (α7nAChR), is suggested as a susceptibility factor for schizophrenia. CHRNA7 has also been genetically linked to the P50 auditory...
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