Maintenance of chondrocyte phenotype during expansion on PLLA microtopographies

Abstract excerpt

Articular chondrocytes are difficult to grow, as they lose their characteristic phenotype following expansion on standard tissue culture plates. Here, we show that culturing them on surfaces of poly(L-lactic acid) of well-defined microtopography allows expansion and maintenance of characteristic chondrogenic markers. We investigated the dynamics of human chondrocyte dedifferentiation on the different...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to 3D Printing in Biomedical Research
• Share to Cell Adhesion Molecules Research
• Share to Osteoarthritis Treatment and Mechanisms