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Article

Three-dimensional microenvironments retain chondrocyte phenotypes during proliferation culture.

Tissue engineering - 1 Jul 2007

Takahashi Tsuguharu, Ogasawara Toru, Asawa Yukiyo, Mori Yoshiyuki, Uchinuma Eiju, Takato Tsuyoshi, Hoshi Kazuto

Abstract excerpt

Although autologous chondrocyte implantation has already been in clinical use, chondrocyte dedifferentiation is problematic during proliferation culture. We attempted a three-dimensional (3D) collagen gel culture under chondrocyte proliferation with repeated passaging to prevent the chondrocytes...

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Identifiers

PMID: 17630901
DOI: 10.1089/ten.2006.0322

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17630901-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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