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Article

Adult human articular chondrocytes in a microcarrier-based culture system: expansion and redifferentiation.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Apr 2011

Schrobback Karsten, Klein Travis Jacob, Schuetz Michael, Upton Zee, Leavesley David Ian, Malda Jos

Abstract excerpt

Expanding human chondrocytes in vitro while maintaining their ability to form cartilage remains a key challenge in cartilage tissue engineering. One promising approach to address this is to use microcarriers as substrates for chondrocyte expansion. While microcarriers have shown beneficial effects for expansion of animal and ectopic human chondrocytes, their utility has not been determined for freshly isolated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20957734
DOI: 10.1002/jor.21264

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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