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Article

Cross-ethnicity tagging SNPs for HLA alleles associated with adverse drug reaction.

The pharmacogenomics journal - 1 Jun 2019

Erlichster Michael, Goudey Benjamin, Skafidas Efstratios, Kwan Patrick

Abstract excerpt

Reduction of adverse drug reaction (ADR) incidence through screening of predisposing human leucocyte antigen (HLA) alleles is a promising approach for many widely used drugs. However, application of these associations has been limited by the cost burden of HLA genotyping. Use of single nucleotide polymorphisms (SNPs) that can approximate ('tag') HLA alleles of interest has been proposed as a cost-effective and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 30093715
DOI: 10.1038/s41397-018-0039-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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