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Article

Human leucocyte antigen-adverse drug reaction associations: from a perspective of ethnicity.

International journal of immunogenetics - 1 Feb 2017

Ghattaoraya G S, Middleton D, Santos E J M, Dickson R, Jones A R, Alfirevic A

Abstract excerpt

Whilst immune-mediated adverse drug reactions (ADRs) are rare, they are potentially life-threatening and present a major problem for clinicians. The underlying mechanisms that cause ADRs are not fully understood although genomewide association studies (GWAS) and case-control investigations have associated human leucocyte antigen (HLA) alleles as risk factors. There is evidence that a patient's ethnic background...

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Identifiers

PMID: 28092143
DOI: 10.1111/iji.12304

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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